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| L-HOMOPHENYLALANINE ETHYL ESTER HCl | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 90891-21-7 |
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| EINECS NO. | ||
| FORMULA | C6H5(CH2)2CH(NH2)CO2C2H5·HCl | |
| MOL WT. | 243.73 | |
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H.S. CODE |
2922.49 | |
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TOXICITY |
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| SYNONYMS | S-(+)-2-Amino-4-phenylbutyric acid ethyl ester hydrochloride; | |
| (S)-alpha-Amino-benzenebutanoic acid ethyl ester hydrochloride; | ||
| DERIVATION |
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| CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white powder | |
| MELTING POINT | 152 - 157 C | |
| BOILING POINT |
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| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions | |
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APPLICATIONS |
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| L-Homophenylalanine is an intermediate for the synthesis of ACE-inhibitors (angiotensin-converting enzyme inhibitor). | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
Off-White crystalline powder | |
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ASSAY (HPLC) |
99.0% min |
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| OPTICAL PURITY |
99.0% min |
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| OPTICAL ROTATION | +40.0° ± 1° (c=2 EtOH) | |
| LOSS ON DRYING | 0.3% max | |
| TRANSPORTATION | ||
| PACKING | 5kgs,
20kgs in can | |
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| In chemical, the prefix homo- indicates the addition of one methyl(CH2) group to the main skeleton. Phenylalanine is an essential amino acid obtained in the levo form by hydrolysis of proteins (as lactalbumin). Branched amino-acids (Valine, Isoleucine and Leucine ) with tryptophan and phenylalanine (aromatic side chain amino acids) contribute to the structure of protein by the tendency of its side chain composed only of carbon and hydrogen to participate in hydrophobic interactions which determines the tertiary structure of the peptide chain. In addition to its role in protein synthesis, it is the metabolic precursor of the non-essential amino acid tyrosine which makes hormones, such as norepinephrine and epinephrine in the normal body. The prefix nor- describes normal structure which has no branched chain of carbon atoms. But in case of norepinephrine, it has one less methylene group than its homologue, epinephrine. Phenylalanine is also converted to phenylethylamine occuring naturally in the brain to elevate mood. It is used to treat depression, inflammation, chronic pain, Parkinson's disease. Phenylalanine is a key intermediate to make aspartame. | ||
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